A study by British researchers has shown that the use of a relatively short follow-up period in the study will lead to over diagnosis becaus
A study by British researchers has shown that the use of a relatively short follow-up period in the study will lead to over diagnosis because of the presence of an early diagnosis of cancer. Related papers published online in May 16, 2013 in the study of breast cancer (B).
The study included women aged 50-79 years in England and Welsh who had a similar age structure and age specific incidence of breast cancer. Then, we screened the 50-69 year old women for 20 years every two years with an exponential distribution of the period of 40 months. In addition to the time period, we do not have other conditions for the incidence of screening.
The results showed that in the screening and screening of the population not compare the age specific incidence and time specific incidence, show the main effects of time period, only can be adjusted through the follow-up of 20 years, including 10 years after the last time of follow-up screening. For women aged 50-69 years of follow-up 20 years, showed an over diagnosis rate of 37%, if the follow-up time extended to 25 years or longer, the transition to a diagnosis of 10%. Because this transition diagnosis is not valid, we will ask for a follow-up of 30 years, including a maximum follow-up period of more than 10 years of follow-up.
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