Research progress of prescription for delaying senility

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The traditional Chinese medicine has rich practical experience and the literature on how to prolong life. In recent years, according to the


The traditional Chinese medicine has rich practical experience and the literature on how to prolong life. In recent years, according to the theory of traditional Chinese medicine (TCM), some effective Chinese medicine for delaying senility have been developed. The traditional Chinese and Western Medicine Research on the aging of Chinese herbal medicine from the kidney, spleen and blood stasis three important ways to study, which is the most important research and application of kidney medicine. The following is only part of the anti-aging formula for example as follows:

(a) an example of Yishen formula

At present, many domestic to kidney yin and Yang, or concurrently with the spleen, tonifying qi and activating blood.

Guilingji the Ming Dynasty Jiajing emperor Shao Yuanjie to alchemist prescriptions, most emperors are very respected, introduced into folk. This recipe is composed of pilose antler, ginseng, radix rehmanniae, hippocampus, eucommia, Cistanche, psoralea fruit, dodder, medlar, sparrow brain, epimedium, clove, halite, amomum fruit, Poria, angelica, Radix asparagi, silkworm and other thirty-three kinds of drugs. The experiment shows that this product, can enhance the adaptability, enhance specific and non-specific immune function; strengthen the regulation of the central nervous system, central excitatory and inhibitory interactions; strengthen the function of the heart, well to directly excite the myocardial; promote sex hormone function and the protection and enhancement of cortical function and liver protection; effect. For example, animal experiments show that it can increase the content of protein and RNA in the liver of mice after normal and carbon tetrachloride poisoning, and inhibit the increase of serum GPT. Elderly people often take this product, can promote the aging of the protein and the important substances in the cell metabolism of nucleic acids, thereby delaying aging.

The Peach-Shaped Mantou pill (Gong Tingfang pill by the Qing Dynasty) galangal seed, rehmannia, ginseng, medlar, walnut meat, asparagus, cinnamon, jujube, angelica etc. more than ten kinds of drug made. Beijing Xiyuan Hospital clinical observation of 157 cases with vitamin E group, medication 8 Monday after drug treatment, fatigue, chills, dizziness, tinnitus, Yaoxisuanruan, insomnia, loss of libido, nocturia and other aging symptoms improved significantly better than vitamin E group. Experiments show that the Peach-Shaped Mantou pill group after administration of plasma lipid peroxidation (LPO) decreased significantly. The serum E2 and T water increased significantly and the E2/T ratio was not changed. The trace elements Zn and Cu were decreased, the Zn/Cu value increased, the memory was enhanced, and the pulmonary ventilation function was enhanced.

Spring return capsule (experience) of the product by the ten herbs Buguzhi, epimedium, Fructus Cnidii, ginseng, pilose antler, polygonatum, hawthorn extract capsules. Guanganmen hospital and other clinical observation of 50 ~ 84 years old, the basic health of the patients (including the control group taking a placebo in 136 cases) in the near future (6 months) and in the control group (n = 19) in the long-term efficacy of the treatment of patients (54 cases). After the administration of "spring" group significantly reduce the symptoms of kidney deficiency, dizziness, tinnitus, insomnia, forgetfulness, chest pain, chills, nocturnal enuresis, loss of appetite, significantly improved fatigue and cold was significantly reduced, a few new hair. The senile plaques disappeared, and the symptoms improved better than the control group. The results showed that the function of heart, kidney, hearing, intelligence and fine after treatment were significantly higher than those before medicine. This product can promote male serum T, serum E2 level and female E2 / T significantly increased, male E2 / T significantly reduced, especially in the kidney yang deficiency group is more significant. The plasma cAMP level, CAMP/cGMP ratio, lymphocyte transformation rate and response to PHA were significantly increased." It can also significantly reduce the growth and MAO activity of serum LPO, and has the effect of lipid-lowering and high HDL.

Canbo oral liquid goods from the Shandong Medical College Affiliated Hospital, according to the "most effective and effective prescription" pill made of Chinese wolfberry. Composed of royal jelly, acanthopanax root, epimedium, sealwort, medlar, radix rehmanniae, Radix Astragali, hawthorn and other drugs. Beijing Xiyuan Hospital and other units for clinical observation of Senile Deficiency Syndrome, 6 to 8 weeks for a course of treatment. After taking the medicine, dizziness insomnia, fatigue, anorexia, brain function and sexual function have improved, physical strength, energy. The results showed that the peak of pulmonary ventilation function was significantly increased, and the ratio of plasma viscosity was significantly decreased, and 3H-TdR uptake was significantly increased in vitro. Animal experiments have proved that this product can significantly increase the level of serum testosterone (T) and estradiol (E2) in female rats, promote and regulate the immune function of mice. The regulation of the central nervous system, enhance the body's ability to adapt and promote hematopoietic function of bone marrow.

Huolisu goods from the Affiliated Hospital of Chengdu College of traditional Chinese medicine "and" according to the "Heshouwu pill pill" Chinese wolfberry chmical process refined. Composed of Astragalus, Polygonum multiflorum, Salvia and other drugs. The Affiliated Hospital of Chengdu College of traditional Chinese medicine clinical observation of 45 cases over the age of 507 (including 220 cases in the control group) basic health. After taking drugs, mental, physical, sleep, appetite and other improvements. The experiment proved that the lymphocyte transformation rate increased, the total number of rosette decreased, the number of live rosettes were significantly increased, superoxide dismutase, catalase and ceruloplasmin increased significantly, serum lipofuscin was significantly less than the control group.

Hjj (experience) of the product by the ten herb rehmannia, flatstem milkvetch, Cynomorium, dodder, Shouwu, Achyranthes, chrysanthemum, calamus and refined. Shanghai junLonghua Hospital and other clinical observation of 45 to 76 years of age in the elderly, the course of treatment for one year, after the immune function enhancement, vital capacity, maximum ventilation increased. Presenile serum creatinine, creatinine clearance rate decreased slightly, slightly increased, part of antinuclear antibodies and rheumatoid factor negative, near visual acuity, visual acuity, bone skin is slightly higher than the former prime. Animal experiments showed that the average survival time of male mice and the average survival rate of male silkworm were significantly prolonged. It can also significantly improve the survival rate, the rate of cell transformation, the percentage of T cell esterase and the rate of rosette. This product can make the seminiferous tube in elderly male mice spermatogenic cells without aging degradation, cell ultrastructure and the young group is similar to that of lipofuscin increase. It can cause the aging of the ovary and uterus of the female aging mice, make the uterus hypertrophy or normal, and the AKP positive reaction of the uterine epithelium. The product can also delay the aging of the femur in elderly mice, such as thinning of bone marrow cavity, and so on. It may promote the formation of bone collagen by improving the sex hormones and improving the energy metabolism.

This product is made of Jinkuishenqiwan radix rehmanniae, Cornus officinalis, yam, Poria, Alisma, paeonol, cinnamon, aconite and refined. Proof of clinical use, this product can reduce fatigue, soreness and weakness of waist and knees, cold extremities, nocturia frequently, constipation and other symptoms. Chiba University in Japan using this product in treatment of senile cataract and fundus changes, visual acuity increased to 60.2%, so that the product can restore the elasticity and function of the lens, and can to some extent restore the body's blood vessels, bone, muscle and brain function, this product has anti-aging effect.

Three treasure pill (experience) whip this product from the Affiliated Hospital of Shandong College of traditional Chinese medicine application of ginseng, pilose antler, penis otariae, deer penis, penis canitis, hippocampus, gecko, cinnamon, aloes, Radix Astragali, Epimedium 40 finish refined form of Chinese medicine. Clinical observation of Yin, this product can enhance the body's immune function, improve sexual function, improve digestion and absorption function, and has anti fatigue and similar two-way regulatory role. In particular, to improve the symptoms of kidney deficiency, anti-aging, has obvious effect.

A large number of studies have shown that trace elements in Chinese traditional medicines containing more kidney, such as zinc (Zn), manganese (Mn), selenium (Se), copper (Cu), germanium (Ge) and other trace elements, promote The new supersedes the old. anti-aging effect. Kidney tonifying drugs can significantly improve cell immunity or inhibit the efficacy of autoantibodies, because it can avoid suffering from cancer and infection and other diseases. In short, kidney tonifying prescription can effectively improve energy, physical strength, intelligence, cold resistance, immune disease resistance, improve the physiological functions of the organs, so that the skin gloss, elasticity, hair loss, etc.. For the prevention and treatment of senile diseases such as coronary heart disease, diabetes, hypertension, hyperlipidemia, chronic bronchitis, etc. have good results.

(two) the study on the prescription of invigorating spleen and replenishing qi

Four Gentlemen Decoction Benfang composed of ginseng, Atractylodes, Poria, licorice. Experiment results show that the regulation of nervous system, increased liver glycogen, regulating blood circulation, promoting bone marrow, enhance immune function and endocrine function, is a common recipe of life.

The eight cake (Qing Dynasty Gong Tingfang) this product is made of ginseng, Chinese yam, lotus seed, coix seed, Poria, lentils, add sugar, two, made. This product was originally the palace food, are fond of men and women, old and young, and as a tonic to increase longevity of. Clinical use for the elderly spleen deficiency, can effectively improve the digestive tract symptoms, but also to improve the aging symptoms, enhance physical fitness. The experimental results show that this product can increase the excretion rate of xylose and the content of serum carotene, enhance the absorption of small intestine and improve the function of spleen and stomach.

Shengmaiyin (Shengmaiye) this product is made of ginseng, ophiopogon root, Schisandra oral liquid or injection. Modern research shows that Shengmai Injection (injection) has strong heart effect, can improve cardiac function, increase cardiac output, have a good effect against shock. For frail elderly, can enhance immune function, reduce blood lipids to adjust blood circulation, but also to improve the intelligence of the elderly. Experimental results show that this product can reduce myocardial oxygen consumption, myocardial metabolism and increased synthesis of myocardial RNA, DNA, protein and glycogen, keep the amount of myocardial ATP at a high level, prolong the animal in low temperature hypoxia survival time. Also has the function of boosting, anti shock, anti infection, can enhance the body's non-specific resistance. There are also lower cholesterol and elevated HDL levels in hyperlipidemic animals.

Healthy qi medicine ginseng, Astragalus and Codonopsis and Chinese medicines aconite, Cynomorium, rehmannia, such as turtle shell match, clinical observation shows that the protein can promote the elderly has the recession and an important intracellular nucleic acid material generation blasphemous, thus delaying senescence. Ginseng with Astragalus membranaceus, Ganoderma lucidum, vitamin E and vitamin A ("Wellcome") can effectively improve the neural decline three symptoms (dizziness, insomnia, fatigue) and brain function. Invigorating spleen and replenishing qi can improve sexual function and improve immunity and disease resistance.

(three) the study of drugs for promoting blood circulation and removing blood stasis

The elderly except five deficiency, often accompanied by blood stasis in superficiality. According to the survey, more than 50% of the elderly with blood stasis symptoms, and a lot of elderly diseases directly related to blood stasis. Drugs for promoting blood circulation and removing blood stasis for health care have good effect on patients with blood stasis syndrome. At the same time for the elderly disease prevention and health care is also very valuable. Mawangdui unearthed tomb No. three of the silk are drugs using blood circulation records. In the early Tang Dynasty some famous doctors such as Zhang Wenzhong, Cui Zhiti et al in the tonic Yannian side, has been promoting blood circulation by removing blood stasis combined drugs. Emperor Qian Long of the Qing Dynasty in longevity, tonifying medicine often with safflower, gold and jade, pangolin and other drugs. The use of anti-aging tonic wine has the effects of Huoxue tongmai. Now, some people advocate the elderly 3G with blood activating drugs of rhubarb can prolong life of the daily work. The experiment has proved that the medicine of promoting blood circulation and removing blood stasis has the function of regulating immunity, enhancing the ability of resisting disease, improving metabolism and lowering blood cholesterol. Drugs for promoting blood circulation and removing blood stasis not only have certain effects on vascular diseases, connective tissue diseases, hemorrhagic diseases and immune diseases, but also play an important role in disease prevention and health care. Especially in improving microcirculation, improve myocardial oxygen supply, prevent thrombosis, dissolve thrombus, prevent atherosclerosis, in addition to low blood coagulation, reduce fibrin deposition, anti-inflammatory, anti infection and other aspects of the role is more significant. According to the physiological characteristics of the elderly, the appropriate use of blood circulation and blood stasis drug health care, for the continuation of the decline of the veteran is very useful.


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