Lynch syndrome diagnosis: 1 you can start from the number of pathological pathological coche (white tablets). Clear of Lynch syndrome in fou
Lynch syndrome diagnosis: 1 you can start from the number of pathological pathological coche (white tablets). Clear of Lynch syndrome in four, MSH2, MSH6, MLH1 gene PMS2 expression by these pathological immune group, and then MSI (MSI); after screening, the expression of MLH1, MSH2, MSH6, PMS2 genes further exclude methylation, BRAF mutation; finally the gene expression of gene sequencing blood check there is no mutation. 2 if you can not get the removal of tumor tissue specimens, you can directly check the blood of the four gene sequencing, no pathological sections of the screen, the four genes may have to be measured, the cost is relatively large.
For the three stage of colon cancer, regardless of whether microsatellite instability, are benefited. For the two stage of colon cancer, due to microsatellite instability in the colon cancer in itself, the prognosis of the two stage is better, chemotherapy may be the survival of the space is not large.
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